Nandana's growing up years were spread across India, America and Europe. She was married to Horst Yorgan Rutstch and was dating Madhu Varma, nephew of director Ram Gopal Varma.
Nandana was first seen on the Indian screen as Rani Mukherjee's jealous seventeen-years-old sister in Black, followed by lead roles in Ram Gopal Verma's My Wife's Murder and Nitin Manmohan's Tango Charlie.
Actress Nandana Sen trained at Lee Strasberg Theatre Institute and Royal Academic of dramatic Art and studied Literature at Harvard University where Nanadana Sen has won John Harvard University Scholarships every year for topping in the class.
Actress Nandana Sen chooses roles that are unpredictable and uncompromisingly real and those films that have unique storyline. Nandana Sen has played the role of enigmatic protagonist Maarya in the prize winning Canadian Drama 'Seducing Maarya' which earned her a Best Actress Nomination in the Quebec Jutra Awards.
Italian filmmaker Italo Spinelli offered Nandana the lead of a tribal woman who's surreptitiously shot nude by a photographer.
The film is based on Bengali litterateur Mahashweta Devi's provocative and controversial story Choli Ke Peeche. The role offered to Nandana was pivotal tempting and challenging.
Nandana was sorely tempted. But doing a full-on topless sequence which is a crucial part of the narrative, so soon after Rang Rasiya, was just not on Nandana's agenda. Nandana made an exception with Ketan Mehta's film. "Rang Rasiya focuses on the increasing critical topic of censorship of art. Remember what happened in Jehangir art gallery last month?
Ketan's film deals entirely with the freedom to paint the human figure in its natural beauty.
The emotional drama as well as the political message of the film revolve around one critical and excessively talked- about scene of Sugandha, the muse, having the courage to break the rules of the time to pose for Ravi Varma (Randeep Hooda) and create a masterpiece of art together."